Cognivia Signal™

Real-Time Behavioral Intelligence for Clinical Trials

The Human Side of Clinical Trials, Made Predictable

Early Detection of Dropout risk

Real-Time Monitoring of Placebo response Drivers

Empower sponsors, CROs, and clinical teams

What Cognivia Signal™ Delivers

Cognivia Signal is a real-time behavioral risk intelligence dashboard for clinical trial teams. By combining participant assessments with machine learning, it helps you detect and mitigate hidden behavioral risks before they disrupt trial performance:

Early Detection of
Dropout risk

Identify participants at risk of dropping out, understand the underlying behavioral drivers, and pinpoint where risk is emerging across sites and countries —

before it impacts trial continuity.

Real-Time Monitoring of Placebo response Drivers

Track and identify psychological and contextual factors influencing placebo response your trial, including expectations and behavioral indicators, to reduce bias and improve data reliability.

With these insights, sponsors, CROs, and clinical teams gain actionable dashboards that support proactive decision-making, minimize disruptions, and protect trial data integrity.

Designed to Solve Real Trial Challenges

Tailor Patient Engagement

Identify patient-specific behavioral risks early and adapt engagement strategies to improve retention and adherence.

Detect Placebo-Drivers

Monitor psychological and contextual factors—such as patient expectations—that influence placebo response, helping reduce bias and strengthen data integrity.

Optimize Site Performance Management

Benchmark behavioral risks across sites, regions, and countries to guide resource allocation and support targeted site management trainings strategies.

Enable Confident Decision-Making

Transform behavioral insights into practical guidance for patient engagement, site management, and trial strategy—building more resilient, data-driven clinical operations.

Adjustment for

Placebo Response Variability

Placebell® is a separate validated solution that complements Cognivia Signal. While Signal provides real-time monitoring of placebo response drivers, Placebell generates individual patient covariates for use in statistical analysis.

This covariate adjustment reduces placebo-driven variability, increases statistical power, and enhances the reliability of efficacy outcomes.

PLACEBELL

Cognivia Signal™ for Precision Healthcare

By integrating patient behavior with existing clinical data, Cognivia Signal:

empowers hospitals, researchers, and policymakers to improve treatment engagement,
reduce readmissions,
and drive better outcomes in high-need areas.

Traditional chart data and social determinants of health often overlook the behavioral dimension.

Cognivia Signal closes this blind spot with predictive, actionable insights - enabling a more human-centered approach to care.

Understand patient differences in your next clinical trial

Increase your trial’s success rates and bring new therapies to patients faster.

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